Modern understanding of the physiological and pathological pain

Abstract

This review presents the morphofunctional peculiarities of the nociceptive system of the body. Based on the
analysis of contemporary literature data considered pathogenetic mechanisms of nociceptive, neuropathic and
psychogenic pain. It is concluded that chronic pain should be combined damage of the peripheral tissues or
structures of the nervous system and disfunction of subcortical and cortical brain structures. Special attention is
paid to disfunction of the ñentral nervous system, wich largery determines the response of the brain to injuri and
the subsequent development of chronic pain.