Medicinal peptide drugs in evidence-based medicine

Authors

  • V. Kh. Khavinson Research Center, St. Petersburg Institute of Bioregulation and Gerontology, St. Petersburg, Russia; I.P.Pavlov Institute of Physiology, St. Petersburg, Russia http://orcid.org/0000-0001-7547-7725
  • I. G. Popovich Research Center, St. Petersburg Institute of Bioregulation and Gerontology, St. Petersburg, Russia; N.N.Petrov National Medical Research Center of Oncology, St. Petersburg, Russia http://orcid.org/0000-0002-9937-025X
  • G. A. Ryzhak Research Center, St. Petersburg Institute of Bioregulation and Gerontology, St. Petersburg, Russia http://orcid.org/0000-0003-2536-1438
  • G. L. Safarova Institute of Regional Economics Problems of the Russian Academy of Sciences, St. Petersburg, Russia http://orcid.org/0000-0003-0289-7977
  • E. A. Vershinina I.P.Pavlov Institute of Physiology, St. Petersburg, Russia; Institute of Regional Economics Problems of the Russian Academy of Sciences, St. Petersburg, Russia http://orcid.org/0000-0002-8873-4409

Keywords:

evidence-based medicine, randomized double-blind placebo-controlled trials, meta-analysis, peptide drugs

Abstract

The article reviews the efficacy and safety of medicinal peptide drugs from the perspective of evidence-based medicine. With regard to medicinal drugs, evidence-based medicine relies on the analysis of information obtained by assessing the benefits and risks of clinical trials and, in particular, randomized double-blind placebo-controlled trials. Based on a systematic review, a metaanalysis, which is a summary and statistical analysis of the results of multiple studies, was performed. This analysis of reported statistical studies proved the unconditional clinical efficacy of medicinal peptide drugs.

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Published

2021-03-10

Issue

Vol. 19 No. 1 (2021): Pathogenesis

Section

Reviews

How to Cite

Medicinal peptide drugs in evidence-based medicine. (2021). Patogenez (Pathogenesis), 19(1), 19-29. https://test.pathogenesis.pro/index.php/pathogenesis/article/view/390