Allelic Polymorphism of the Genes of Estrogen Metabolism Enzymes in case of Genital Endometriosis

Authors

  • K S Kublinskiy Siberian State Medical University, Russia, 634050, Tomsk, 2 Moskovsky trakt, e-mail: rector@ssmu.ru
  • V V Novitskiy Siberian State Medical University, Russia, 634050, Tomsk, 2 Moskovsky trakt, e-mail: rector@ssmu.ru
  • O I Urazova Siberian State Medical University, Russia, 634050, Tomsk, 2 Moskovsky trakt, e-mail: rector@ssmu.ru

Keywords:

genital endometriosis, allelic polymorphism of the genes of estrogen metabolism enzymes

Abstract

Up-to-date molecular genetic research methods have revealed that women predisposed to genital endometriosis possess Allele G and Genotypes AG and GG of the polymorphic option 4889G of the CYP1A1 gene as well as Allele A and Genotypes CA and AA of the polymorphic option C-734A of the CYP1A2 gene. The polymorphism of the promoter regions of the SULT1A1 (G-638A) and SULT1E1 (C-174T) genes is not associated with genital endometriosis in women.

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Published

2015-09-30

Issue

Vol. 13 No. 3 (2015): Pathogenesis

Section

Original investigations

How to Cite

Allelic Polymorphism of the Genes of Estrogen Metabolism Enzymes in case of Genital Endometriosis. (2015). Patogenez (Pathogenesis), 13(3), 41-44. https://test.pathogenesis.pro/index.php/pathogenesis/article/view/32