Activities of leukocyte elastase and alpha-1 proteinase inhibitor in patients with atopic dermatitis

Authors

  • M. V. Tarasova Institute of General Pathology and Pathophysiology, Moscow, Russia
  • M. V. Ovsyannikov Rostov State Medical University, Rostov-on-Don, Russia
  • E. N. Volkova Institute of General Pathology and Pathophysiology, Moscow, Russia

DOI:

https://doi.org/10.25557/2310-0435.2018.04.153-156

Keywords:

atopic dermatitis, leukocyte elastase, α1-proteinase inhibitor

Abstract

Summary. Leukocyte elastase activity has been shown to be increased in patients with atopic dermatitis and to correlate with the disease severity. However, this increase is not always accompanied by an adequately increased activity of the α1-proteinase inhibitor (α1-PI). Evidence suggest that the decreased α1-PI activity is an unfavorable prognostic sign of changes in BP that contribute to further progression of the destructive process.

Downloads

Published

2018-12-11

Issue

Vol. 16 No. 4 (2018): Pathogenesis

Section

Brief reports

How to Cite

Activities of leukocyte elastase and alpha-1 proteinase inhibitor in patients with atopic dermatitis. (2018). Patogenez (Pathogenesis), 16(4), 153-156. https://doi.org/10.25557/2310-0435.2018.04.153-156