Ways of correction immune homeostasis changes during pregnancy assessing the state of health of offspring

Authors

  • S. G. Morozov Institute of General Pathology and Pathophysiology, Moscow, Russian Federation
  • E. N. Kozhevnikova Institute of General Pathology and Pathophysiology, Moscow, Russian Federation
  • O. B. Kadasheva N.E.Bauman City Clinical Hospital №29, Moscow, Russian Federation
  • N. P. Petkevich Institute of General Pathology and Pathophysiology, Moscow, Russian Federation
  • A. V. Lobanov Branch of the M.M.Shemyakin –Yu.A.Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Pushchino of Moscow Region, Russian Federation
  • A. N. Murashev Branch of the M.M.Shemyakin –Yu.A.Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Pushchino of Moscow Region, Russian Federation
  • A. A. Sidyakin N.E.Bauman City Clinical Hospital №29, Moscow, Russian Federation
  • I. A. Zakharova Institute of General Pathology and Pathophysiology, Moscow, Russian Federation
  • I. E. Gribova N.E.Bauman City Clinical Hospital №29, Moscow, Russian Federation
  • V. M. Inshakova Institute of General Pathology and Pathophysiology, Moscow, Russian Federation

Keywords:

immunoneurophysiology

Abstract

It has been shown that children born to mothers with low levels of aATs to MBP, protein S100, ASVR-C, MR-C during pregnancy, who did not receive immunotherapy, are more likely to be born prematurely, in asphyxia, with lower birth rates (body weight, growth, Apgar score), which requires their long-term observation in the maternity hospital (up to 2 weeks) or transfer to children's hospitals with diagnoses such as PPNS, IUGR, IVH, prematurity. In children from the comparison group, changes in NSH are more often recorded, they are more pronounced and require a longer time for their compensation, therefore, these children are more often observed by a neurologist with diagnoses such as PPNS or hypoxic-ischemic CNS damage, episyndrome, etc. Children in this group more often suffer from pneumonia due to the failure of the immune system.

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Published

2023-03-06

Issue

Section

Original investigations

How to Cite

Ways of correction immune homeostasis changes during pregnancy assessing the state of health of offspring. (2023). Patogenez (Pathogenesis), 12(3), 20-26. https://test.pathogenesis.pro/index.php/pathogenesis/article/view/618

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